The various travel sites may have different fare rates so do not make an assumption that they have the same fares for the various airlines. Most especially on international flights, the differences could be several hundred dollars lower or higher; it really depends. So, you better check on all the popular travel sites and online agencies if possible. Take help of travel assistant or travel coordinator if required.
Most sites have a flexible fare search and this can be helpful if the date you will be flying doesn't matter. For instance, if it doesn't matter for grandma if you will be visiting her on September instead of August you could probably save some money if you were to adjust your travel dates when fares are cheaper and lower since it is not peak season.
Combining weekend fares and great deals can be realized by people if they combine these fares on their itinerary. The fares of two airlines can be combined but just ensure that you provide an allowance for any delays that may occur.
Sign up for newsletters that may provide you with information with regards special fare rates and discounted or reduced prices. Such fare alerts will enable you to avail of promotional offers that could save you a lot of money on airfare. All those on travel job will be able to guide you.
Usually purchasing a package that includes the airfare plus the hotel can save you money instead of just purchasing the airfare and hotel accommodation alone. Such a package is ideal when there are two people traveling as most hotel rates are based on a double occupancy. This is practically perfect for a last-minute travel decision.
Reduced fare options can often be posted early morning or on weekends on airline web sites. Usually such short promotional offers last only for a few hours as seats can actually sell quickly.
It would also be very much helpful if you check for rates as often as necessary. In the same way as the stock market is very much unpredictable, airfare rates can shoot up or shoot down. If you are that serious on saving precious dollars, have the persistence to regularly check everyday if possible. There are separate corporate travel agents to help you out if you are going on a corporate trip.
Lastly, choose an airline that provides a refund for the difference in case the fare rate suddenly drops and you were able to purchase it at a much higher rate days before.